The compound shown a dose-dependent reaction in decreasing stress stages as measured via the elevated moreover maze and open field assessments
This brings about muscle relaxation, sedation, and anxiolysis. Bromazolam also influences cell signaling pathways by modulating the action of GABA_A receptors, which can affect gene expression and mobile metabolism
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Comparison with Very similar Compounds Bromazolam is analogous to other benzodiazepines which include alprazolam, flubromazolam, and clonazolam. it is exclusive because of the presence of the bromine atom at the eight-posture, which distinguishes it from its analogs:
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Bromazolam binds to the GABA-A receptor, manufacturing a conformational adjust and potentiating its inhibitory effects
These metabolic pathways are important for knowledge the pharmacokinetics and likely toxicity from the compound.
Bromazolam is usually a strong benzodiazepine, renowned for its sizeable consequences over the central anxious process. Scientists favor it for learning the intricate workings of benzodiazepines on brain function and behavior.
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In phase I metabolism, Bromazolam is hydroxylated and demethylated by cytochrome P450 enzymes. In phase II metabolism, the metabolites are conjugated with glucuronic acid or sulfate, facilitating their excretion
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